Prof Edwin Madala, an analytical biochemist in the University of Venda’s Faculty of Science, Engineering and Agriculture in Limpopo, South Africa, earned his Ph.D. in Biochemistry from the University of Johannesburg under Prof Ian Dubery’s guidance. Initially a lecturer and later a senior lecturer at UJ’s Department of Biochemistry, Edwin moved to the University of Venda in April 2018. There, he continued his focus on plant chemistry research, particularly in plant metabolomics, unraveling the complexity introduced by chemical modifications like glycosylation and isomerization of plant metabolites. Edwin’s expertise lies in employing LC-MS techniques to study plant metabolites, using nutraceutical plants as models. His current research delves into understanding the mechanistic pathways leading to trans-cis isomer formation triggered by light exposure, a phenomenon exacerbated by climate change-induced excessive sunlight. These isomers, with isobaric mass but